Right Heart Failure as “Sole” Presentation of Carcinoid Syndrome

نویسندگان

  • Pramod Theetha Kariyanna
  • Mirela Andrei
  • Cherif Abdelmalek
  • Ajay Kundra
  • Boris Avezbakiyev
  • James E. O’Donnell
  • Alexander Rozin
چکیده

Carcinoid tumors are rare neuroendocrine tumors that arise from neural crest amine precursor uptake decarboxylation cells. Most of carcinoid tumors originate in the midgut. The vasoactive secretory products of carcinoid tumor upon metastasis to liver reach systemic circulation as they bypass the metabolism by liver. 50% of patients with carcinoid syndrome eventually develop carcinoid heart disease. We here present a rare case of carcinoid tumor with metastasis to liver that solely presented with right heart failure. The patient did not have any symptoms of typical carcinoid syndrome features such as flushing, diarrhea, and bronchoconstriction.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Carcinoid heart disease revealed by cyanosis with both right and left valvular involvement: a case report

BACKGROUND Carcinoid heart disease is a frequent complication of carcinoid syndrome. It is related to the release by the carcinoid tumor and/or its metastases of bioactive substances such as serotonin. It is characterized by right-sided valvular involvement and can lead to right-sided heart failure. It is a prognostic factor of carcinoid syndrome. CASE PRESENTATION We report the case of a 53-...

متن کامل

Carcinoid Heart Disease: From Pathophysiology to Treatment--'Something in the Way It Moves'.

Carcinoid heart disease (CHD) is a rare cardiac manifestation occurring in patients with advanced neuroendocrine tumours and the carcinoid syndrome, usually involving the right-sided heart valves and eventually leading to right heart failure. The pathophysiology of CHD is still obscure and believed to be multifactorial, as a variety of vasoactive substances secreted by the tumour appear to be i...

متن کامل

A Case of Carcinoid Syndrome Due to Malignant Metastatic Carcinoid Tumor with Carcinoid Heart Disease Involving Four Cardiac Valves

BACKGROUND Carcinoid tumor, benign, low-grade malignant, and high-grade malignant, can be associated with the release of vasoactive substances that cause symptoms including cutaneous flushing, diarrhea, and bronchospasm. In 50-60% of patients with carcinoid syndrome, the vasoactive substances cause fibrosis of the pulmonary and tricuspid heart valves which lead to regurgitation and right-sided ...

متن کامل

Echocardiographic imaging of tricuspid and pulmonary valve abnormalities in primary ovarian carcinoid tumor

Carcinoid is a rare malignancy originating from enterochromaffin cells and is clinically characterized by flushing, diarrhea and bronchospasm, due to secretion of vasoactive substances. A dreaded complication is carcinoid heart disease, which mainly affects right cardiac chambers, resulting in thickened, immobile and retracted tricuspid and pulmonary valves. In the current report, a case of a 6...

متن کامل

Carcinoid Heart Disease in a Primary Ovarian Carcinoid.

UNLABELLED Ovarian carcinoids are very rare, and only their insular form is associated with carcinoid syndrome. We herein describe a case report of an elderly woman who presented with typical carcinoid syndrome, which is routinely characterized by right-sided heart failure, diarrhoea, flushes, and other common manifestations. Further examination and biochemical testing of the patient confirmed ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2016